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Why/How Does IT Work
​ We at Plant Medicine believe it's important for people to understand how the psychedelic plant medicine helps and works to alleviate their symptoms of anxiety, depression, or medication existing depression or PTSD.
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It is important to know we a dealing with like but serperate neural transmitters with plant medicines.
1 Pychedelic mushrooms - Psilocybin which converts into the psychoactive molecule psilocinPysillium
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2. Bufo - MeO-DMT (5 Methoxy-N,N dimethyltryptamine)
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3 Ayahuasca - DMT coupled with a vine that produces an MAO inhibitor so the DMT is absorbed into the body and brain. The primary active don't break my fucking window man. I'm just working.
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4. KAMBO - Although combo does not have any psychoactive properties it creates instantsneious nausea, vomiting, sweating, rapid heartbeat, and flushing, followed by deep fatigue and later a sense of clarity or energy.
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5. Peyote -alkaloid mescaline, one of the oldest known naturally occurring psychedelics.
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Main action: Mescaline activates serotonin 5-HT2A receptors in the brain, producing profound alterations in perception, emotion, and consciousness.
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Duration: Effects typically last 8–12 hours.
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6 Bufo - 5-MeO-DMT - producing profound alterations in perception, emotion, and consciousness.
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7. San Pedro -
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How do the Plant Medicines make us Better
How Psychedelics Affect the Default Mode Network (DMN)
One of the key ways psychedelics support healing and transformation is through their effect on the Default Mode Network (DMN) — a complex system in the brain linked to self-identity, ego, and repetitive thought patterns.
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Recent research shows that substances like psilocybin and LSD can temporarily suppress activity in the DMN, quieting the rigid sense of self that often reinforces depression, anxiety, and addictive behaviors. This interruption allows for moments of ego dissolution, enhanced creativity, and more open, flexible problem-solving — helping individuals see themselves and the world with renewed clarity and connection.
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The general idea is that certain psychedelics — such as LSD, psilocybin, mescaline, or DMT — increase activity throughout the brain but decrease activity in the DMN. It’s been likened to the concept of “defragmenting a computer.”
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When we suppress the DMN, it essentially turns off the reducing valve that controls the brain’s lower regions and allows for a higher entropy state [6]. This effectively transitions us closer toward a primary state of consciousness and allows more memory information to bubble up to the higher regions of the brain.
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We become more in touch with the way we’re feeling, we experience a greater level of empathy towards others, we’re more creative, and it opens us up to new ideas and information we may have previously ignored.
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In simple terms, psychedelics temporarily increase entropy and reduce the rigidity of thoughts, which provides a unique opportunity to access and integrate new information and update our beliefs and assumptions in a positive and life-affirming way.
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This is considered one of the primary ways psychedelics can reduce addictive tendencies, anxiety, obsessive-compulsive disorder, or other byproducts of rigid thought patterns.
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Anxiety and Rumination
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Medication Resistant Depression
Eating Disorders and other addictions
Spiritual Oriuentation
Fear of Death
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